1′-Butyl-2-methyl-1′,2,2′,3,4,9-hexahydrospiro[benzo[f]isoindole-1,3′-indole]-2′,4,9-trione
نویسندگان
چکیده
In the title compound, C(24)H(22)N(2)O(3), the indoline and pyrrole-fused naphtho-quinone units are both essentially planar [r.m.s. deviations = 0.042 (3) and 0.133 (3) Å, respectively]. The pyrrole ring adopts a C-envelope conformation. The dihedral angle between the mean planes of the two five-membered rings is 89.94 (9)°. The O atoms deviate from the mean planes of the pyrrolidine and naphthalene rings by 0.0311 (2), 0.2570 (2) and 0.1669 (2) Å. In the crystal, C-H⋯O inter-actions generate dimers with R(2) (2)(16) and R(2) (2)(18) graph-set motifs. The carbonyl O atom is involved in bifurcated hydrogen bonding. C-H⋯π inter-actions also occur.
منابع مشابه
(1S,3R)-3-Isobutyl-2,3-dihydrospiro[benzo[f]isoindole-1,3′-indoline]-2′,4,9-trione methanol monosolvate
In the title compound, C(23)H(20)N(2)O(3)·CH(3)OH, the hexa-hydro-1H-benzo[f]isoindole and indoline rings are planar, with maximum deviations of 0.092 (1) and -0.095 (1) Å, respectively. The dihedral angle between these two rings is 88.03 (4)°. An O-H⋯N inter-action links the main mol-ecule and the methanol solvent mol-ecule. An intra-molecular C-H⋯O inter-action forms an S(6) ring motif. In th...
متن کاملSynthesis and structure of the mercury chloride complex of 2,2′-(2-bromo-5-tert-butyl-1,3-phenylene)bis(1-methyl-1H-benzimidazole)
In the title mercury complex, catena-poly[[di-chlorido-mercury(II)]-μ-2,2'-(2-bromo-5-tert-butyl-1,3-phenyl-ene)bis-(1-methyl-1H-benzimidazole)-κ2N3:N3'], [HgCl2(C26H25BrN4)] n , the HgII atom is coordinated by two Cl atoms and by two N atoms from two 2,2'-(2-bromo-5-tert-butyl-1,3-phenyl-ene)bis-(1-methyl-1H-benzimidazole) ligands. The metal cation adopts a distorted tetrahedral coordination g...
متن کاملIntroduction of a new complex imide system into the structure of LCAPs. The synthesis and a 5-HT1A, 5-HT2A and D2 receptor binding study.
A series of 17 long-chain arylpiperazines containing bulky, complex imide systems (5,8-dimethyl-3b,9-epoxy-(3a,4,5,6,7,8,9,9a)-octahydro-1H-benzo[e]isoindole-1,3(2H)-dione or 4,9-diphenyl-4,9-epoxy-3a,4,9,9a-tetra-hydro-1H-benzo[f]isoindole-1,3(2H)-dione) was synthesized and evaluated for their affinity for serotonin 5-HT1A, 5-HT2A and dopamine D2 receptors. Most of the new compounds showed mod...
متن کاملSHORT COMMUNICATION INTRODUCTION OF A NEW COMPLEX IMIDE SYSTEM INTO THE STRUCTURE OF LCAPs. THE SYNTHESIS AND A 5-HT1A, 5-HT2A AND D2 RECEPTOR BINDING STUDY
A series of 17 long-chain arylpiperazines containing bulky, complex imide systems (5,8-dimethyl-3b,9-epoxy-(3a,4,5,6,7,8,9,9a)-octahydro-1Hbenzo[e]isoindole-1,3(2H)-dione or 4,9-diphenyl-4,9-epoxy-3a,4,9,9a-tetrahydro-1H-benzo[f]isoindole-1,3(2H)-dione) was synthesized and evaluated for their affinity for serotonin 5-HT , 5-HT and dopamine D receptors. Most of the new compounds showed moderate ...
متن کاملStructure of the mercury(II) mixed-halide (Br/Cl) complex of 2,2′-(5-tert-butyl-1,3-phenylene)bis(1-pentyl-1H-benzo[d]imidazole)
The mercury(II) complex of 2,2'-(5-tert-butyl-1,3-phenyl-ene)bis-(1-pentyl-1H-benz-imidazole), namely catena-poly[[dihalogenido-mercury(II)]-μ-2,2'-(5-tert-butyl-1,3-phenyl-ene)bis-(1-pentyl-1H-benzimidazole)-κ2N3:N3'], [HgBr1.52Cl0.48(C34H42N4)], 2, has a polymeric structure bridging via the N atoms from the benzimidazole moieties of the ligand. The compound crystallizes in the ortho-rhom-bic ...
متن کامل